[AccessD] Runtime error '2424' - do I care? should I care?

One computer in our office keeps giving this error message when 
running a search of a zip code field (using a wildcard).  I've never 
had it happen to me, so I don't know how to look for the problem.  If 
you choose End, it finds what you're searching for.  The other option 
is Debug.  Haven't gone there because I don't know what I'd do when I 
got there.  Waiting for the error to come up again and I'll see what 
happens on Debug.  It's not consistently appearing and I can't 
replicate it on my computer no matter how I copy her searches.  Could 
the error be specific to that computer?  I know it shouldn't be 
happening, but that doesn't necessarily translate into something I 
need to focus on while busy with other projects.  Do I need to spend 
time looking into this?  Thanks for any help!
Susan Jones